Pallidotomy

Interest in GPi target for dystonia was prompted by the observation of remarkable amelioration of off-dystonia and dyskinesias in PD patients who underwent pallidotomy. Most of the published experience is limited to patients with either generalized or hemidystonia. There are no studies addressing specifically the benefit of this procedure for Cervical Dystonia (CD). However, a number of patients with generalized dystonia had CD that improved as the result of surgery. Most reports emphasize a delayed onset of improvement over a couple month after surgery. Patients with bilateral symptoms require a bilateral procedure. Interestingly, bilateral pallidotomy for dystonia has not been associated with speech and cognitive complications observed with this procedure in Parkinson's patients. However the numbers are too small to draw a definitive conclusion.

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